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| Arizona Diamondbacks — Last 10 | 7-3 Away: 27-30 |
| Cleveland Guardians — Last 10 | 3-7 Home: 27-27 |
| Travel Risk | High |
| Rest Advantage | Neutral |
| Arizona Diamondbacks Bullpen (L3D) | 2 games Medium fatigue |
| Cleveland Guardians Bullpen (L3D) | 2 games Medium fatigue |
AI review runs at pick publication time.