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| Chicago Cubs — Last 10 | 7-3 Away: 25-22 |
| Cincinnati Reds — Last 10 | 3-7 Home: 21-26 |
| Travel Risk | High |
| Rest Advantage | Neutral |
| Chicago Cubs Bullpen (L3D) | 3 games High fatigue |
| Cincinnati Reds Bullpen (L3D) | 3 games High fatigue |
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