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| Chicago White Sox — Last 10 | 6-4 Away: 32-38 |
| Houston Astros — Last 10 | 5-5 Home: 34-36 |
| Travel Risk | High |
| Rest Advantage | Neutral |
| Chicago White Sox Bullpen (L3D) | 3 games High fatigue |
| Houston Astros Bullpen (L3D) | 3 games High fatigue |