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| Colorado Rockies — Last 10 | 3-7 Away: 18-37 |
| San Diego Padres — Last 10 | 6-4 Home: 28-24 |
| Travel Risk | High |
| Rest Advantage | Neutral |
| Colorado Rockies Bullpen (L3D) | 2 games Medium fatigue |
| San Diego Padres Bullpen (L3D) | 2 games Medium fatigue |
AI review runs at pick publication time.