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| New York Yankees — Last 10 | 6-4 Away: 33-23 |
| Chicago White Sox — Last 10 | 6-4 Home: 32-19 |
| Travel Risk | High |
| Rest Advantage | Neutral |
| New York Yankees Bullpen (L3D) | 3 games High fatigue |
| Chicago White Sox Bullpen (L3D) | 3 games High fatigue |
AI review runs at pick publication time.