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| Pittsburgh Pirates — Last 10 | 8-2 Away: 36-39 |
| Chicago Cubs — Last 10 | 4-6 Home: 41-31 |
| Travel Risk | High |
| Rest Advantage | Neutral |
| Pittsburgh Pirates Bullpen (L3D) | 3 games High fatigue |
| Chicago Cubs Bullpen (L3D) | 2 games Medium fatigue |
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