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| San Diego Padres — Last 10 | 8-2 Away: 36-40 |
| Colorado Rockies — Last 10 | 2-8 Home: 31-42 |
| Travel Risk | High |
| Rest Advantage | Neutral |
| San Diego Padres Bullpen (L3D) | 3 games High fatigue |
| Colorado Rockies Bullpen (L3D) | 3 games High fatigue |
AI review runs at pick publication time.