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| San Francisco Giants — Last 10 | 3-7 Away: 22-40 |
| Cleveland Guardians — Last 10 | 3-7 Home: 29-33 |
| Travel Risk | Low |
| Rest Advantage | Neutral |
| San Francisco Giants Bullpen (L3D) | 2 games Medium fatigue |
| Cleveland Guardians Bullpen (L3D) | 2 games Medium fatigue |