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No guaranteed wins · Informational use only · Bet responsibly
| San Francisco Giants — Last 10 | 4-6 Away: 20-35 |
| San Diego Padres — Last 10 | 7-3 Home: 29-24 |
| Travel Risk | Low |
| Rest Advantage | Neutral |
| San Francisco Giants Bullpen (L3D) | 3 games High fatigue |
| San Diego Padres Bullpen (L3D) | 2 games Medium fatigue |