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No guaranteed wins · Informational use only · Bet responsibly
| San Francisco Giants — Last 10 | 4-6 Away: 26-49 |
| St. Louis Cardinals — Last 10 | 4-6 Home: 36-39 |
| Travel Risk | Low |
| Rest Advantage | Neutral |
| San Francisco Giants Bullpen (L3D) | 3 games High fatigue |
| St. Louis Cardinals Bullpen (L3D) | 3 games High fatigue |