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| St. Louis Cardinals — Last 10 | 3-7 Away: 26-23 |
| Toronto Blue Jays — Last 10 | 4-6 Home: 26-30 |
| Travel Risk | Low |
| Rest Advantage | Neutral |
| St. Louis Cardinals Bullpen (L3D) | 3 games High fatigue |
| Toronto Blue Jays Bullpen (L3D) | 2 games Medium fatigue |
AI review runs at pick publication time.